A106: Rituximab Use in Pediatric Antiphospholipid Antibody Positive Patients

Rituximab use in late antibody-mediated rejection

The only randomized controlled trial on the treatment of AMR is the effects of rituximab on acute antibodymediated rejection in renal transplantation (RITUX ERAH) trial, which compared rituximab with placebo in 38 patients along with standard treatment with PP and IV IG. This treatment did not detect any significant difference in outcome between the groups at the end of 1 year. However, the stu...

Higher Incidence of Pulmonary Hypertension in Antiphospholipid Antibody Positive Lupus.

BACKGROUND Antiphospholipid antibodies (APAs) are detected in 30-40% of SLE patients, but only few develop APLA syndrome. Incidence of pulmonary hypertension (PH) is reportedly high in APA positive patients; however, Indian data is missing. MATERIALS AND METHODS This cross-sectional, observational study was conducted from Jan 2009 - Dec 2011, on 50 SLE patients, fulfilling ACR criteria. SLE p...

Screening for Pulmonary Hypertension in Antiphospholipid Antibody Positive Lupus Erythematosus.

Group 2: PH due to left heart diseases. Group 3: PH due to respiratory diseases. Group 4: Chronic thrombo-embolic PH. G r o u p 5 : P H w i t h u n c l e a r multifactoral mechanisms. The pathogenes is o f PH in SLE can be multifactorial , but pulmonary arterial hypertension (PAH) is the commonest cause. This is characterised by increase in mean pulmonary arterial pressure (mPAP) ≥25 mmHg at re...

Improving management of pregnancy in antiphospholipid antibody-positive women.

using intrathecal rituximab in two pediatric patients with ptld